ABSTRACT
Objective: To investigate the effect of sampling positions in nucleic acid test for COVID-19 on test results.
ABSTRACT
Objective: To analyze a cluster outbreak of COVID-19 associated with exposure to a shopping mall in Jinan City, investigate the possible transmission chain, and provide reference for further prevention and control.
ABSTRACT
Objective There were 47 confirmed cases of coronavirus disease 2019 (COVID-2019) reported in Jinan City from January 23 to February 11, 2020. Since February 25, 2020, there were no confirmed cases reported in Jinan City for 14 consecutive days. In order to provide reference for future epidemic prevention and control, we analyzed the current epidemic situation and epidemiological characteristics. Methods The demographic, clinical and epidemiological characteristics of confirmed cases in Jinan City were evaluated with descriptive analysis and family clusters were traced. Results 74.5% of 47 confirmed cases were clinical common type, and 24 (51.1%) were cured and discharged. No death occurred. Fever (66.0%) was the first dominant symptom. CT showed 82.1% of the cases were bilateral pneumonia. The distribution of cases was similar between male and female. Most patients (70.2%) aged 20 to 59 years, 83.0% lived in the central urban area, and 40.4% had a history of Wuhan exposure before onset. Five of 10 family cluster outbreaks were sourced from Wuhan exposure. 70.2% (33 cases) of 47 cases were related to the family cluster outbreaks. Conclusion The epidemic prevention and control work in Jinan City has achieved phased results. Preventing importation from surrounding areas and high incidence risk areas is still the focus of future efforts.
ABSTRACT
Coronavirus disease 2019 (COVID-19) is currently a global concern, and the psychological impact cannot be overlooked. Our purpose was to evaluate the anxiety and depression in spinocerebellar ataxia (SCA) patients during the pandemic and to analyse the influencing factors. We conducted an online questionnaire survey among 307 SCA patients from China and selected 319 healthy people matched by sex and age as the control group. The questionnaire included general information, the self-rating anxiety scale (SAS), and the self-rating depression scale (SDS). The relevant factors included COVID-19 risk factors, age, sex, body mass index (BMI), educational background, disease course, score on the scale for the assessment and rating of ataxia (SARA), Mini-mental State Examination (MMSE) and International Cooperative Ataxia Rating Scale (ICARS). The proportion of SCA patients with anxiety was 34.9%, and the proportion with depression was 56.7%. The SAS and SDS scores of the SCA patients were significantly higher than those of the control group (SAS: 45.8 ± 10.1 vs. 40.6 ± 8.9, P < 0.01; SDS: 55.1 ± 12.2 vs. 43.6 ± 11.9, P < 0.01). In SCA3, the risk of exposure to COVID-19, educational level, disease course and the severity of ataxia may be factors affecting patients' mental health. More attention should be paid to the mental health of SCA patients during the COVID-19 pandemic.